Kambo can either be received in a private session or in a circle-setting with multiple participants. Kambo should only be received from a properly trained practitioner administering and supervising the treatments at all times.
A Kambo treatment is intense but fast. The physical effects are immediate and can be uncomfortable, and in most cases involve purging (vomiting). Therefore, before a Kambo treatment you will need to fast for at least 6 hours so as not to have any food in the stomach, then right before the beginning of the treatment you will be asked to drink a large amount of water, which will act as a carrier for the purging. Not every Kambo treatment is necessarily unpleasant however, and certainly no two treatments are ever the same. The effects are over within 20 – 40 minutes.
When the process is finished, you may feel tired and need to rest. Within a short time, usually an hour or so, you will feel much better and you can drink and eat normally again. Usually within a day or so, depending on your state of health, you will start to feel the real benefits.
Sometimes, in situations where Kambo is used to treat chronic health conditions, an effect called the Herxheimer reaction (or herxing) can occur, where, because of a strong detoxification process, a condition can temporarily get worse before it gets better. This is a natural, well-studied and well-understood part of many healing processes.